Multi-voxel Magnetic Resonance Spectroscopy of Neurotransmitters at 3 Tesla in Healthy Adults
M Dölken, A Mennecke, A Stadlbauer, T Struffert, T Engelhorn, G Meritxll, A Doerfler, T Hammen · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2009 · Heft 05
Bibliografische Angaben
Zusammenfassung
Ziele: The objective of this study was to determine how metabolite levels (total N-acetyl aspartate (tNAA), glutamate plus glutamine (Glx), total choline (tCho), myo-inositol (mI) and total creatine (tCr)) vary across brain regions in healthy subjects, including gray and white matter differences. Methode: Using the multi-voxel technique with a voxelwise phantom calibration at a 3 Tesla MRI Scanner, metabolite levels of 26 healthy controls (10 men, 17 women, mean age 29 years) were obtained from the hippocampi, within gray matter sites of the the basal ganglia (Thalamus, Putamen), from the Insula Kortex, Cingulum…