Continuous heparin infusion and in-line filter in peripherally placed percutaneous central venous catheters

Objective: To evaluate the effectiveness of heparin combined with in-line filters for the reduction of occlusion rate, increase of elective catheter removal and prolongation of catheter life time of peripherally placed percutaneous central venous catheters (PCVCs) in neonates. Study design: Prospective observational study in neonates with PCVC, comparing heparin (1 IU/ml) combined with in-line filters versus no heparin/no in-line filters. Primary objectives were to evaluate the rate of catheter occlusion and elective catheter removal. Secondary objectives were the evaluation of catheter life time and rates of ph…