O/E LHR and O/E FLV as predictors for chronic lung disease in infants with congenital diaphragmatic hernia

Aims: Prenatal measurement of the observed-to-expected lung-to-head ratio (O/E LHR) and the observed-to-expected fetal lung volume (O/E FLV) may be useful in predicting mortality in patients with congenital diaphragmatic hernia (CDH). Prenatal measurements to predict pulmonary morbidity, such as chronic lung disease (CLD), are lacking. Objective: To determine if O/E FLV and O/E LHR are useful prenatal predictors of CLD in infants with CDH. Methods: Newborns with CDH born between 2002 and 2007 were eligible for inclusion. Data on survival, pulmonary status and basic patient characteristics were collected. CLD, de…