Spontaneous Monochorionic Five-Amniotic Quintuplet Pregnancy

Spontaneous quintuplet pregnancies are rare and can arise from polyovulation or simultaneous embryo splitting. In a historic sample of 71 spontaneous quintuplet pregnancies only 2 sets survived up to adolescence (1). According to Hellin's formula are expected to occur in 1/41 million births. Among them the incidence of monochorionic (MC) 5-amniotic (5A) quintuplets are even much less frequent. In none of the up-to now described case reports the placenta has been analyzed as MC 5A, and never a prenatal diagnosis had been made before. We here report on the ultrasound findings at first diagnosis at 12 + 4 gestation…