Tumor Necrosis Factor α, Interleukin 1 β in Amniotic Fluid and Plasma in Normal and Pr-Eclamptic Nigerian Women

Objective: To investigate if markers for activation of the immune system are present in patient with Pre-eclampsia by assessing maternal plasma and amniotic fluid for tumor necrosis factor α and Interleukin 1α. Study design: n=30 women with severe pre-eclampsia composed the study group (Group A) An antepartum comparison group was composed of healthy nulliparous patient n=30 not in labour and matched for gestational age (Group B). Another control group consisted of term nulliparous patients in labour with uneventful pregnancies (Group C). Maternal plasma samples were collected from all patients at recruitment and…