Distribution and localization of the nerve elements in the liver of different mammals

Aims: Changes in the density and localization of nerve fibres (especially the sympathetic and Substance P (SP) -containing nerve fibres) might play a role in the inflammation of the different organs. The aim of the present work was to look for a species where the innervation pattern is similar to the human liver. Materials and methods: The different nerve elements were detected by ABC immunohistochemistry in the liver of a rat, a cat, a guinea-pig and a human being. The density of the different nerve terminals were analysed semiquantitatively. Results: Large number of Neuropeptide Y (NPY) and dopamine β-hydroxyl…