Parvo-Virus B19 Infection: Evidence for intrahepatic long-term persistence but no association with disease progression in chronic hepatitis C
C Wang, A Heim, V Schlaphoff, PV Suneetha, H Jiang, M Krüger, P Fytili, K Stegmann, T Bock, MP Manns, H Wedemeyer · Zeitschrift für Gastroenterologie · 2008 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims Parvovirus B19 is the causative agent for fifth disease. Recently, it was reported that PV-B19 may play an important role in the pathogenesis of HBV in Vietnamese patients. We here aimed to investigate whether PV-B19 infection may be a co-factor for disease progression in European patients with chronic hepatitis C. Methods 91 serum samples from well characterized and histologically staged chronic hepatitis C patients and 50 serum samples from chronic hepatitis B patients were investigated for the presence of PV-B19 antibodies and PV-B19 DNA (real-time PCR). Moreover, 50 explanted livers and 32 liver biopsy…
