Cortical motor excitability in adults with ADHD: Results of a TMS-study

Introduction: The Attention Deficit-/Hyperactivity Disorder (ADHD) persists into adulthood in up to 60% of the cases (1). During transition into adulthood, motor hyperactive behaviour is changed as well as quantitatively as also qualitatively (2, 3). Pathophysiologically, disturbances of cortical motor excitability have been discussed. Motor cortical excitability can investigate non-invasively with the help of transcranial magnetic stimulation (TMS). Studies in ADHD children have shown impairments of inter-hemispheric inhibition, intra-cortical inhibition (short interval cortical inhibition, SICI) and intra-cort…