Differentiation of H2O2 and Lactate in bronchial and alveolar Exhaled Breath Condensate Fractions

Introduction: In former studies an elevation of hydrogen peroxide and/or lactate in breath condensate due to pulmonary inflammation has been reported. A reduction of H2O2 due to anti inflammatory treatment in exacerbated COPD was also observed. Methods: The new ECoScreen 2 enables the fractionated collection of breath condensate into disposable bags. The system has the capability to discard air from mouth cavity and a pre-selected part from air stream from sampling. Results: In 30 healthy volunteers and 9 untreated patients with exacerbated COPD and/or asthma and 11 patients with anti inflammatory treatment, fra…