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Expression of the Bone Morphogenetic Protein Receptor 1A Gene (BMPR1A) in Adipose Tissue and BMPR1A Genetic Variation are Associated with Human Obesity

Y Böttcher, D Schleinitz, H Unbehauen, N Klöting, K Ruschke, B Enigk, A Tönjes, S Wolf, YH Tseng, M Blüher, M Stumvoll, P Kovacs · Diabetologie und Stoffwechsel · 2008 · Heft 04

Dokument
863194
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Diabetologie und Stoffwechsel
Autor:innen
Y Böttcher, D Schleinitz, H Unbehauen, N Klöting, K Ruschke, B Enigk, A Tönjes, S Wolf, YH Tseng, M Blüher, M Stumvoll, P Kovacs
Ausgabe
Heft 04 / 2008
Seiten
–
Erschienen: 2008-04-18 00:00:00
ISSN
1861-9002
DOI
10.1055/s-2008-1076221

Zusammenfassung

Family of bone morphogenetic proteins (BMP) is involved in regulation of adipogenesis. We measured the mRNA expression of BMP members in paired samples of visceral and subcutaneous adipose tissue from 198 subjects and examined its relation to obesity. Amongst others, mRNA expression of the human bone morphogenetic protein receptor 1A (BMPR1A) was significantly increased in both visceral and subcutaneous adipose tissue of 51 overweight (BMI>25 and 30kg/m2) subjects compared with 56 lean subjects (BMI

Schlagworte

Diabetologie und Stoffwechsel