Placental mesenchymal stem cells as potential grafts for peripartum osteogenic and neural regeneration
S Mohr, BC Portmann-Lanz, A Schoeberlein, R Sager, DV Surbek · Ultraschall in der Medizin - European Journal of Ultrasound · 2008 · Heft 05
Bibliografische Angaben
Zusammenfassung
Objective Recently we could show that mesenchymal stem cells (MSCs) exist in placental tissue. These cells could be differentiated towards both mesodermal and neurogenic lineages. In regard with possible autologous transplantation we evaluated the potential of these cells. Aims: 1.To manufacture an osteogenic composite graft consisting of placental MSCs and chorion scaffold for site-specific perinatal repair of bone defects. 2.To assess the neurogenic potential of these cells in regard with possible neuroregeneration in the premature infant. Study Design We manufactured a scaffold from human chorionic membrane o…
