CareLit Fachartikel

Vemurafenib effectively controlled Chemotherapy-refractory Intrahepatic Cholangiocarcinoma with BRAF V600E Mutation: a case report and literature review

Mengyuan Yang, Liuhong Wang, Ying Yuan · Zeitschrift für Gastroenterologie · 2022 · Heft 12 · S. 1787-1791

Dokument
863586
CareLit-ID
Jahr
2022
Publikation
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
Mengyuan Yang, Liuhong Wang, Ying Yuan
Ausgabe
Heft 12 / 2022
Jahrgang 60
Seiten
1787-1791
Erschienen: 2022-12-01 00:00:00
ISSN
0044-2771

Zusammenfassung

Abstract Background Chemotherapy is the first treatment option for local advanced or metastatic intrahepatic cholangiocarcinoma (ICC). However, after first-line chemotherapy, there is no standard second-line treatment or targeted agents for these patients. Case presentation Here we present an advanced ICC patient who has received radical resection and adjuvant chemotherapy (gemcitabine + cisplatin). But the no evidence of disease (NED) was maintained for only 6 months after the end of chemotherapy. He then received palliative surgery, radiotherapy and systemic chemotherapy (Tegafur+Oxaliplatin (SOX) and Nab-Pacl…

Schlagworte

Vemurafenib intrahepatisches Cholangiokarzinom BRAF Fallbericht Übersicht Intrahepatic Cholangiocarcinoma Case report Review Zeitschrift für Gastroenterologie