Acute Disturbance of Axonal Excitability after controlled Alcohol Intake

Introduction: Acute alcohol intake causes clinical symptoms of hypoexcitability of nerval structures like the cerebellum and in higher concentrations, of the cerebrum and the brain stem, eventually leading to coma. Chroniv level alcohol consumption often leads to axonal peripheral neuropathy. From anecdotical reports and self observation peripheral nerve conduction, i.e. hypoexcitability immediately after alcohol intake is likely disturbance. Material and Methods: Peripheral nerve excitability was measured in five healthy human subjects aged 21 to 40 years by applying multiple measures of excitability. The media…