Association between Insulin-like growth factor-I and the incidence of metabolic syndrome: Results from the Study of Health in Pomerania

Background: Recently no longitudinal data are available regarding the association of insulin-like growth factor I (IGF-I) and metabolic syndrome (MetS). Cross sectional studies showed an inverse association between IGF-I and the risk of impaired glucose tolerance or diabetes mellitus (DM). Only one prospective study among patients with myocardial infarction demonstrated a lower risk of DM among patients with high baseline IGF-I suggesting a protective effect of IGF-I against the development of MetS. The aim of the present study was to investigate the longitudinal association between IGF-I and MetS. Methods: Data…