The pharmacovigilance-center FAKOS – Detection of drug induced agranulocytosis, immune thrombocytopenia, hepatitis, pancreatitis, LongQT-Syndrome and Torsade de pointes

Background and Aim: Adverse drug reactions (ADR) are an important cause of morbidity and mortality. The Berlin Pharmacovigilance Center PVZ-FAKOS uses an active surveillance approach to identify hospitalised patients with serious rare, however often drug-induced diseases. Aim of FAKOS is to assess potential drug risks for the following diseases: acute Agranulocytosis (AGR), Immune Thrombocytopenia (ITP), acute Hepatitis (HEP), acute Pancreatitis (PAN), and LongQT Syndrome/Torsade de pointes (LQT/TdP). Materials and Methods: FAKOS recruits patients (age ≥18) with AGR and ITP (2000–2009), HEP and PAN (2002–2009) a…