A clinical staging system for cirrhosis: a multicenter cohort study of 1858 patients
M Dollinger, G D'Amico, C Villanueva, AK Burroughs, R Planas, R Sola, P Cales, M D'Amico, I Garupera, M Garcovich, A Zipprich, RM Morillas, I Cirera, G Roquin, WE Fleig, A Colomo, N Canete, MA Alvarez, J Boursier, L Pasta · Zeitschrift für Gastroenterologie · 2011 · Heft 01
Bibliografische Angaben
Zusammenfassung
A staging system for cirrhosis has been recently proposed based on varices, ascites and bleeding (J Hepatol 2006;44: 217–31). We aimed at validating the concept of clinical stages for cirrhosis and assessing the role of hepatocellular carcinoma (hcc), encephalopathy (pse) and jaundice. A total of 1858 patients from prospective cohorts were included in the study at the seven participating centers. Survival analysis was performed by the Kaplan-Meier method by individual patient data. Predictive accuracy for 1-year mortality of Pugh score and MELD across stages was assessed by c-statistics. Etiology was from HBV 6%…