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Subthalamic γ Activity Depends on Movement Amplitude and Velocity

A. Bock, J. Huebl, S. Siegert, V. Litvak, G.H. Schneider, A. Kupsch, A.A. Kühn · Klinische Neurophysiologie · 2011 · Heft 03

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Jahr
2011
Publikation
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
A. Bock, J. Huebl, S. Siegert, V. Litvak, G.H. Schneider, A. Kupsch, A.A. Kühn
Ausgabe
Heft 03 / 2011
Seiten
–
Erschienen: 2011-03-10 00:00:00
ISSN
1434-0275
DOI
10.1055/s-0031-1272681

Zusammenfassung

Introduction: Event-related synchronization (ERS) in gamma band activity (60–80Hz) recorded from the subthalamic nucleus (STN) contralateral to the moved hand has been shown in Parkinson's disease (PD) patients. Here, we correlate the degree of gamma band ERS to parameters of motor performance such as speed and movement amplitude, and its change with dopaminergic medication. Methods: In 16 patients (4 females) undergoing deep brain stimulation (DBS) for severe PD, subthalamic local field potentials of adjacent bipolar contact pairs of each DBS electrode were recorded, while patients performed forearm pronation m…

Schlagworte

Klinische Neurophysiologie