Imaging-based versus Invasive Treatment Response Assessment: Comparison of Radiological and Histopathological Local Response to Neoadjuvant Therapy in High-Risk Soft Tissue Sarcom…

Ziele: To compare radiological tumour response assessment systems for treatment monitoring and to investigate to what extent there is an agreement between radiological and histopathological response in patients with soft tissue sarcomas (STS) undergoing neoadjuvant treatment. Radiological response according to RECIST and WHO criteria was compared and correlated to histopathological response based on necrosis and fibrosis. Methode: 63 patients with STS were evaluated. Radiological response according to RECIST and WHO was assessed by analysing CT or MRI examinations of the primary tumour before and after 4 cycles…