Proton MR-Spectroscopy in Focal Cortical Dysplasia (FCD)
W Block, F Träber, AM Sprinkart, S Greschus, J Gieseke, M Malter, H Urbach, H Tschampa, H Schild · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2011 · Heft 12
Bibliografische Angaben
Zusammenfassung
Background/Purpose: Focal cortical dysplasia is probably the most common cause of therapy-refractory epilepsy in children, and also a frequent cause of epilepsy in adults. Pathologically an FCD is a malformation of cortical development; several subtypes can be differentiated. The FCD subtype with balloon cells (FCD type IIb), which we have investigated, is considered a distinct clinical, neuropathological, and MRI entity. MRI characteristics are cortex thickening and a funnel-shaped subcortical hyperintensity (in T2 and FLAIR) tapering towards the lateral ventricle. Lesions can be subtle and easily overlooked. P…