Identification of liver specific genes using next generation sequencing technology

Introduction: The next generation sequencing technology offers an entirely new perspective for clinical research and will speed up personalized medicine. In this work this new technology was used to identify a gene profile highly specific for healthy liver tissues, which could deal as a diagnostic tool to distinguish between a healthy or diseased liver.Material and Methods: Initially next generation sequencing data were downloaded from EMBL (ENA ERP000257). This genome-wide expression compendium originates from eleven, healthy, human tissue samples pooled from multiple donors. The tissues are as followed: adipos…