Frequency and characterization of pain in adult patients with Pompe disease

Aims: Pain in adult patients with Pompe disease (glycogenosis type II) is a common complaint, but has not yet been well characterized. Methods: In this multicentre cross sectional study, patients were recruited by the German and UK section of the International Pompe Association and the Erasmus Medical Center. The pain onset, its intensity and qualities, its impact on the functional ability and depression parameters as well as its relation to disease severity and pain medication were analysed by questionnaires (Brief Pain Inventory (BPI), Rotterdam Handicap Scale (RHS), Gardner-Medwin-Walton-Scale (GMWS), Hospita…