Improving quality of life in patients with metastatic prostate cancer following one cycle of 177Lu-PSMA-617 radioligand therapy: a pilot study
Milka Marinova, Reza Alamdar, Hojjat Ahmadzadehfar, Markus Essler, Ulrike Attenberger, Martin Mücke, Rupert Conrad · Nuklearmedizin - NuclearMedicine · 2020 · Heft 06 · S. 409-414
Bibliografische Angaben
Zusammenfassung
Abstract Introduction To evaluate the clinical therapeutic response of PSMA targeted radioligand therapy with 177Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer. The current study analyzed disease-related quality of life (QoL) in patients undergoing PSMA therapy with a special focus on the association with simultaneous PSA response. Methods Thirty patients (age range 50–87 years, median 73.5 years) undergoing 177Lu-PSMA-617 therapy from 2014 to 2016 at our institution were included in this pilot study. Health-related QoL was assessed by EORTC QLQ-C30 questionnaire filled in at baseli…