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Vergleich der biologischen Strahlenwirkung des β--Emitters 186Re mit 662 keV Photonenstrahlung auf die humane B-Zelllinie BV-173

Jennifer Staudt, Christian Happel, Wolfgang Tilman Kranert, Benjamin Bockisch, Frank Grünwald · Nuklearmedizin - NuclearMedicine · 2021 · Heft 06 · S. 438-444

Dokument
869137
CareLit-ID
Jahr
2021
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Nuklearmedizin - NuclearMedicine
Autor:innen
Jennifer Staudt, Christian Happel, Wolfgang Tilman Kranert, Benjamin Bockisch, Frank Grünwald
Ausgabe
Heft 06 / 2021
Jahrgang 60
Seiten
438-444
Erschienen: 2021-12-01 00:00:00
ISSN
0029-5566
DOI
10.1055/a-1560-2079

Zusammenfassung

Abstract Aim Aim of the study was to determine the effects of the β--emitter 186Re and 662 keV photon radiation in order to compare the biological effects of low dose rate (186Re) to high dose rate irradiation. Methods Prae-B-lymphocytes were exposed to 662 keV photon radiation or incubated with a liquid solution of 186Re. Cell count and viability were compared over the observation period of seven days, survival curves constructed and analysed at time of lowest cell-viability. Results Biphasic cell survival curves resulted for both radiation types. Survival curves were obtained at 24 h for photon radiation and 7…

Schlagworte

Biologische Strahlenwirkung B-Zelllinie BV-173 186Re Biological radiation effect low dose rate irradiation Nuklearmedizin - NuclearMedicine