Synthesis of Prospective Multiple Time Points F-18 FDG PET Images from a Single Scan Using a Supervised Generative Adversarial Network

AbstractThe cumulative activity map estimation are essential tools for patient specific dosimetry with high accuracy, which is estimated using biokinetic models instead of patient dynamic data or the number of static PET scans, owing to economical and time-consuming points of view. In the era of deep learning applications in medicine, the pix-to-pix (p2 p) GAN neural networks play a significant role in image translation between imaging modalities. In this pilot study, we extended the p2 p GAN networks to generate PET images of patients at different times according to a 60 min scan time after the injection of F-1…