Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C i…
O Goetze, M Breuer, J Oellsner, R Youssef, A Geier, M Fried, A Weber, B Müllhaupt · Zeitschrift für Gastroenterologie · 2014 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background: Ishak and METAVIR scores are the most widely accepted descriptive non quantitative scoring systems for evaluation of fibrosis in patients with chronic hepatitis C infection. The amount of hepatic collagen as a surrogate for fibrous tissue can be measured by computer assisted digital image analysis in histological sections. The aim of this cross-sectional study was to describe the association of hepatic collagen quantification with histological METAVIR staging and with the indirect fibrosis markers transient elastography (FS) and 13C methacetin breath (MBT). Methods: 60 patients with chronic hepatitis…
