In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

We recently demonstrated that CA19 – 9 values in patients with primary sclerosing cholangitis (PSC) depend on genotype of fucosyltransferase 2 and 3 (FUT2/3). CA19 – 9 serum levels might be influenced by biliary obstruction or infection. Therefore, we aimed to evaluate the influence of cholestasis and cholangitis on CA19 – 9 in dependency on FUT2/3 genotype. In cancer-free patients with well-defined PSC, maximum CA19 – 9 values before liver transplantation were obtained. Laboratory markers of cholestasis (alkaline phosphatase (ALP), total bilirubin, gamma glutamyl transferase (GGT)) and inflammation (C-reactive…