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PET functional imaging of deep brain stimulation in the healthy rat brain

N Van Den Berge, V Keereman, C Vanhove, P van Mierlo, B Van Nieuwenhuyse, B Vandeghinste, R Raedt, P Boon, S Vandenberghe, R Van Holen · Klinische Neurophysiologie · 2014 · Heft 03

Dokument
873017
CareLit-ID
Jahr
2014
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Neurophysiologie
Autor:innen
N Van Den Berge, V Keereman, C Vanhove, P van Mierlo, B Van Nieuwenhuyse, B Vandeghinste, R Raedt, P Boon, S Vandenberghe, R Van Holen
Ausgabe
Heft 03 / 2014
Seiten
–
Erschienen: 2014-03-12 00:00:00
ISSN
1434-0275
DOI
10.1055/s-0034-1371301

Zusammenfassung

Question: Deep Brain Stimulation (DBS) is a promising therapy for neurological and psychiatric disorders. However, the underlying mechanism of action of DBS remains unknown. Functional imaging studies in the rat brain, such as 18F-fluorodeoxyglucose-Positron Emission Tomography (18F-FDG-PET), reflecting changes in neural activity, may help elucidate the mechanism of action of DBS throughout the brain and potentially improve clinical outcome. To our knowledge, no DBS 18F-FDG-PET studies have been done in the healthy rat brain. The aim of this study was to investigate the effect of hippocampal DBS on regional cere…

Schlagworte

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