Identification of ADA as a Biomarker for Atypical Epstein Barr Virus Infection in Children
Ting Shi, Linlin Huang, Wangsheng Zhang, Wenxin Shi, Jiahui Wu, Yuanxi Bian, Yanqun Jiang, Jianmei Tian · Klinische Pädiatrie · 2023 · Heft 04 · S. 221-227
Bibliografische Angaben
Zusammenfassung
Abstract Objective This study aims to explore the ability of adenosine deaminase (ADA) to discriminate atypical Epstein Barr virus (EBV) infection in children from acute febrile illness. Methods All children admitted to the Children’s Hospital of Soochow University between 2018 and 2019, who were acute febrile patients and subjected to the plasma EBV-DNA polymerase chain reaction (PCR) and indirect immunofluorescence (IIF) assay for EBV-specific antibodies assays. The diagnostic value of each detection index was compared by the area under the ROC curve. Results In children with atypical Epstein Barr virus infect…