Role of non-invasive serologic methods in the diagnosis of chronic liver diseases

Introduction: All the chronic liver diseases activate the producing of connective tissue and lead to fibrosis. The measure of fibrosis accurately correlate with the damage of the liver. Researches on fibrosis resulted in the conclusion that fibrosis and – in certain degree – cirrhosis can be reversible. So the evaluation of fibrosis is of capital importance in the diagnosis, prediction of prognosis and therapy. Discussion: Diagnostic methods in the evaluation of fibrosis: 1. biopsy, 2. serologic markers, 3. imaging methods (US, MR, transient elastography, MR spectroscopy, MR elastography). In our lecture we anal…