Imaging cilial motion by endoscopic optical coherence microscopy

Endoscopic imaging gives minimally invasive access to the airways and can provide important diagnostic information. We have shown that optical coherence microscopy (OCM), the combination of confocal microscopy and optical coherence tomography is able to image airway tissue with subcellular resolution. Due to its high imaging speed and lack of tissue damage OCM is a promising technique for clinical imaging if it can be integrated into endoscopic imaging devices. Here, we present endoscopic OCM imaging of airway tissue using a rigid GRIN lens based endoscopes. Beating motion of cilia and particle transport was vis…