Risk factors and outcome in patients with primary sclerosing cholangitis with persistent biliary Candidiasis

Introduction: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease. Identification of high-risk patients displays an important issue for clinicians. Beside bacterial infections some studies suggested a strong influence of fungal infections on survival in PSC patients. Aim: To analyze incidence, risk factors and liver-dependent survival in PSC patients with persistent biliary Candidiasis. Methods: Of 405 consecutive patients with the diagnosis of PSC that were admitted to our Department during the time period of 2002 and 2012, 150 patients with endoscopic therapy and routine bile cultures w…