Galectin 2 expression in placentas of pre-eclamptic patients

Introduction: Preeclampsia (PE), is well known as a pregnancy specific disorder associated with maternal inflammation and insufficient placentation. Galectin 2 (gal-2) has been shown to have important regulatory functions in monocyte and macrophage function as well as in angiogenesis. Methods: Placental tissues were obtained from 14 women with regular pregnancies and 13 women with PE, with a mean date of delivery in the PE group of 34 ± 3.2 and in the control group 39 ± 1.4 weeks of gestation. The tissue samples were stained for immunohistochemistry and immunofluorescence and analyzed using the IRS score to eval…