Disseminated tumor cells from the bone marrow of patients with metastatic breast cancer
A Hartkopf, D Stefanescu, M Wallwiener, M Hahn, EF Solomayer, S Becker, T Fehm, S Brucker, FA Taran · Geburtshilfe und Frauenheilkunde · 2014 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background: Disseminated tumor cells (DTCs) from bone marrow (BM) of primary breast cancer patients are an early indicator of hematogenous cancer spread. There is, however, few known about the role of DTCs in metastatic breast cancer (MBC). Methods: The DTC-Status was evaluated in MBC patients, treated between 01/2001 and 07/2012 at Tuebingen University Hospital, Germany, by immunocytochemistry and cytomorphology. Progression free survival (PFS) and overall survival (OS) were analyzed using univariate and multivariate analysis. Results: DTC were detected in 64 of 178 (36%) patients. Presence of DTCs was not asso…
