Replacement of oxytocin bolus administration by infusion: influences on adverse postpartum outcome

Objective: Postpartum haemorrhage (PPH) represents a leading cause of maternal morbidity and mortality. Giving oxytocin after birth reduces the risk for PPH. It has never been tested, whether different methods of oxytocin administration affect maternal outcome. This study aims to compare the incidence of postpartum complications in women receiving an infusion or a bolus of oxytocin after vaginal delivery. Methods: Retrospective study including 1765 women delivering singletons vaginally at term. Patients were classified into two groups; those who received 5 IU of oxytocin as an intravenous bolus or as a 100 ml-in…