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Genetic breast cancer susceptibility variants and prognosis in the prospectively randomized SUCCESS A trial

A Hein, L Häberle, AB Ekici, MP Lux, B Rack, T Weissenbacher, U Andergassen, C Scholz, L Schwentner, A Schneeweiss, R Lorenz, H Forstbauer, H Tesch, I Schrader, M Rezai, W Janni, MW Beckmann, RM Weinshilboum, L Wang, PA Fasching · Geburtshilfe und Frauenheilkunde · 2014 · Heft 09

Dokument
874553
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Jahr
2014
Publikation
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DOI
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Bibliografische Angaben

Zeitschrift
Geburtshilfe und Frauenheilkunde
Autor:innen
A Hein, L Häberle, AB Ekici, MP Lux, B Rack, T Weissenbacher, U Andergassen, C Scholz, L Schwentner, A Schneeweiss, R Lorenz, H Forstbauer, H Tesch, I Schrader, M Rezai, W Janni, MW Beckmann, RM Weinshilboum, L Wang, PA Fasching
Ausgabe
Heft 09 / 2014
Seiten
–
Erschienen: 2014-09-05 00:00:00
ISSN
0016-5751
DOI
10.1055/s-0034-1388571

Zusammenfassung

Large scale genotyping studies have identified more than 70 single nucleotide polymorphisms (SNPs) that are associated with breast cancer (BC) risk. The knowledge about risk factors that are associated with prognosis is however growing much slower. Aim of this study was therefore to investigate nine known breast cancer risk SNPs for their prognostic relevance. Breast cancer risk SNPs rs17468277(CASP8), rs2981582(FGFR2), rs13281615(8q24), rs3817198(LSP1), rs889312(MAP3K1), rs3803662(TOX3), rs13387042(2q35), rs4973768(SLC4A7) rs6504950(COX11) of 1,687 BC patients from a random sample from the SUCCESS A study were…

Schlagworte

Geburtshilfe und Frauenheilkunde