Gender linked counter effect of N. sativa seeds and P. ovata husks on fibrosis in NAFLD

Nonalcoholic fatty liver disease (NAFLD) is an emerging hepatic disorder both in males and females of Asian countries mainly linked with high fat diet (HFD) consumption. The purpose behind the current project was to assess the counter effect of fat reducing agents against HFD induced fibrosis. Forty males (M) and forty female (F) Rattus norvegicus were subdivided into four groups (0, I, II and III) depending upon different diet compositions. Group 0 was fed on 100% rat chow, Groups I, II and III were provided with HFD. The diets of group II and III were supplemented with 5% Nigella sativa seeds or Plantago ovata…