Baseline gamma-GT levels within the normal range predict high virologic response rates in treatment-naïve patients undergoing boceprevir triple therapy for HCV genotype 1 (G1) inf…
P Buggisch, HF Löhr, G Teuber, H Steffens, MR Kraus, C John, PR Geyer, B Weber, T Witthöft, A Herrmann, M Hoesl, U Naumann, E Zehnter, D Hartmann, B Dreher, M Bilzer · Zeitschrift für Gastroenterologie · 2015 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background: A considerable number of patients (pts) with chronic HCV G1 infection will present with elevated serum gamma-GT levels. However, the impact of gamma-GT elevation on virologic response to boceprevir triple therapy has not been investigated until yet and was therefore the aim of the present interim analysis of the German NOVUS observational study. Methods: From April 2012 until January 2014, 536 pts with G1 infection were recruited in the ongoing NOVUS study by 97 practices and hospitals in Germany. Pts were treated with pegylated interferons (PegIFN) and ribavirin (RBV) together with BOC for 24 to 44…
