Relation of conspicuous biochemical results in first trimester screening and pregnancy complications

Background: Early detection of high risk pregnancies is an important matter in modern obstetrics in order to avoid severe pregnancy complications. Aim of the posed study is to analyze the relevance of conspicuous biochemical results in first trimester screening concerning the pregnancy outcome. We assume that differed levels of biomarkers PAPP-A, free βHCG and PlGF can provide information about the risk of developing hypertensive complications (gestational hypertension, preeclampsia, eclampsia, HELLP-syndrome), intrauterine growth restriction, intrauterine fetal death, abruption of the placenta, gestational diab…