Association of CFTR mutations with Cystic Fibrosis related Diabetes (CFRD) in Germany and Austria: a multicentre analysis from the DPV registry
K Laubner, N Scheuing, M Bauer, K Konrad, E Lilienthal, N Lorenzen, T Poeplau, A Teeken, A Thon, J Seufert, RW Holl, M Schebek · Diabetologie und Stoffwechsel · 2015 · Heft 04
Bibliografische Angaben
Zusammenfassung
Background: CF-related diabetes (CFRD) is a common comorbidity in cystic fibrosis (CF) and associated with negative outcome and increased mortality. In this study, we aimed to investigate current demographics of CFRD and the association of CFRD with C transmembrane conductance regulator (CFTR) genotypes. Methods: Until September 2014, data of 777 patients with CFRD were included in the DPV-registry. Since 2013 the participating centres document the type of CFTR mutation additionally to diabetes-related parameters. Of 105 patients the CFTR mutation was available. Descriptive statistics were carried out using SAS…
