Association between interleukin-6 and motor nerve conduction in individuals with newly diagnosed diabetes: results from the German Diabetes Study
I Schamarek, C Herder, B Nowotny, K Straßburger, M Carstensen-Kirberg, P Nowotny, A Strom, S Püttgen, K Müssig, J Szendroedi, D Ziegler, M Roden · Diabetologie und Stoffwechsel · 2015 · Heft 04
Bibliografische Angaben
Zusammenfassung
Objective: Biomarkers of subclinical inflammation are associated with distal sensorimotor polyneuropathy, but their relationship to objective electrophysiological measures has not been assessed. Therefore, the aim of this study was to investigate associations between inflammation-related biomarkers and nerve conduction velocity (NCV) in the German Diabetes Study (GDS). Methods: Motor and sensory NCV were assessed in 513 patients with newly diagnosed type 1 and type 2 diabetes (n = 331 and 182, respectively; age 47 ± 14 years, 64.5% male, BMI 29.5 ± 6.4 kg/m2, duration since diagnosis 185 ± 98 days). Associations…