Improved endoscopic optical coherence microscopy for imaging of humans airways in patients

We recently developed an endoscopic optical coherence microscope (eOCM) prototype and successfully imaged the nasal epithelium of humans. Based on the experience from previous tests in probands we designed a new compact and userfriendly eOCM-prototype for clinical use. The first eOCM prototype consisted of high power broadband supercontinuum light source, a customized 400nm spectrometer and a rigid semi-contact endoscope with a length of 45 mm and a diameter of 3 mm mounted on a handheld probe. We achieved a lateral and axial resolution of less than 1.5 µm with a grin lens based objective (0.5 NA). Imaging speed…