[18F]-PSMA-1007-PET for evaluation of kidney function
Philipp Rassek, Michael Schäfers, Kambiz Rahbar, Philipp Backhaus · Nuklearmedizin - NuclearMedicine · 2023 · Heft 04 · S. 244-251
Bibliografische Angaben
Zusammenfassung
Abstract Purpose Prostate-specific membrane antigen (PSMA) is present in the proximal tubule cells of the kidneys. This results in high renal tracer uptake in PSMA-PET, which may contain useful information on renal function. As part of the evaluation for [177Lu]-PSMA therapies, patients undergo PSMA-PET and additional [99mTc]-mercapto-acetyltriglycine (MAG3) scintigraphy to assess renal function. Aim of this study was to evaluate estimation of renal function with [18F]-PSMA-1007-PET/CT (PSMA-PET) by comparison to timely MAG3-scintigraphies. Materials and Methods We retrospectively investigated 73 prostate cancer…