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Novel biomarkers for risk stratification in pulmonary arterial hypertension

T Zelniker, L Uhlmann, S Spaich, J Friedrich, M Preusch, FJ Meyer, HA Katus, E Giannitsis · Pneumologie · 2016 · Heft 02

Dokument
878802
CareLit-ID
Jahr
2016
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Pneumologie
Autor:innen
T Zelniker, L Uhlmann, S Spaich, J Friedrich, M Preusch, FJ Meyer, HA Katus, E Giannitsis
Ausgabe
Heft 02 / 2016
Seiten
–
Erschienen: 2016-02-09 00:00:00
ISSN
0934-8387
DOI
10.1055/s-0036-1572121

Zusammenfassung

Background: Risk stratification in pulmonary arterial hypertension (PAH) is paramount to identify individuals at highest risk of death. So far, there are only limited parameters for prognostication in patients with PAH. Materials & Methods: Ninety-five patients with confirmed PAH were included in the present analysis and followed for a total of 4 years. Blood samples were analyzed for serum levels of NT-proBNP, hsTnT, proANP, GDF-15, sFlt-1, and PlGF. Results: Twenty-seven patients (28.4%) died during a follow-up of 4 years. Levels of all tested biomarkers except for PlGF were significantly elevated in non-survi…

Schlagworte

Pneumologie