Long-term impact of achieving sustained virologic response(SVR)by IFN-free DAA treatment in patients with advanced liver disease.
K Kozbial, S Moser, R Al-Zoairy, R Schwarzer, H Laferl, C Freissmuth, R Stern, S Beinhardt, A Stättermayer, A Maieron, M Gschwantler, P Ferenci, H Hofer · Zeitschrift für Gastroenterologie · 2016 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background and aims: IFN-free antiviral treatment with DAAs improves liver function in many patients with cirrhosis already at the end of therapy, however, results of long-term follow-up are not yet known. The aim of this study was to evaluate patients' virological and clinical outcomes at follow-up week 48 after interferon-free DAA therapy. Methods: 159patients with cirrhosis (n = 135) or advanced fibrosis (F3, n = 24) with SVR after IFN-free DAA therapy and at least48 weeks of treatment-free follow up were evaluated (m/f = 99/60; mean age 56.8 ± 10.5yrs; genotype [GT-1: 128, GT-2: 2, GT-3: 18; GT-4: 11], cirrh…
