Intestinal inflammation and motility: How does STW 5 influence this?
L Marx, D Grundmann, D Schreiber, D Simon, A Braun, W Burkhardt, C Xu, H Abdel-Aziz, O Kelber, KH Schäfer · Zeitschrift für Phytotherapie · 2016 · Heft 06
Bibliografische Angaben
Zusammenfassung
The herbal combination phytomedicine STW 5 (Iberogast) is a proven compound to ameliorate symptoms of functional dyspepsia and irritable bowel syndrome, both diseases being discussed to be based on a subclinical inflammation [1]. The effect of STW 5 on intestinal inflammation and motility was investigated in the small intestine of adult mice. A proinflammatory cytokine cocktail (IL1β, TNFα, IFNγ) was injected into the supporting blood vessel arcades of small intestinal segments to measure the intestinal motility under local induced inflammation in the presence and absence of STW 5 (+/-). Additionally, the effect…
