Sox2 expression in the myenteric plexus in the caecum of postnatal and adult mouse

The enteric nervous system originates from the enteric neural crest stem cells and a subset of Schwann cell precursors, which colonize the intestine at embryonic stages. Enteric neural crest stem cells differentiate into glial cells and neurons, whereas the Schwann cell precursor subset differentiates into neurons. The expression of Sox2 was currently described in enteric nervous system progenitor and glial cells from embryonic to adult stage. In this study, the expression of Sox2 in the myenteric plexus of the mouse caecum was investigated. The caecum is an important site of fermentation and harbors a huge numb…