Application of Monsel's solution after cervical biopsy: a randomized trial

Objective: To estimate the efficacy and side effects of Monsel's solution for hemostasis after cervical punch biopsy. Methods: In a prospective, randomized trial, we compared application of Monsel's solution versus a ‘wait and see’ approach in women undergoing cervical punch biopsies. The primary endpoint was vaginal bleeding (VB) after 15 minutes measured by scoring a sanitary pad with a 5-level pictogram. Secondary endpoints were VB after 3, 6, and 24 hours (5-level pictogram), subjective estimation of overall VB during 24 hours, pain after 15 minutes and subjective estimation of overall pain after 24 hours, a…