Premenopausal Trabecular Bone Loss is Associated with a Family History of Fragility Fracture
J. C. Prior, C. L. Hitchcock, Y. M. Vigna, V. Seifert-Klauss · Geburtshilfe und Frauenheilkunde · 2016 · Heft 08 · S. 895-901
Bibliografische Angaben
Zusammenfassung
Abstract Introduction: Although a fragility fracture family history (FFFH+) has repeatedly been shown to be associated with lower bone mineral density (BMD), its relationship to human BMD change is unclear. Animal research, however, documented that different purebred strains within rodent species have wide ranges in rates of bone acquisition during growth as well as in change post-ovariectomy. Our objective was to compare the rate of premenopausal spinal trabecular BMD change between women with and without a general family history of fragility fracture. Participants and Methods: Healthy premenopausal community w…