CareLit Fachartikel

Impact of Increased Activated Protein-C Resistance, Decreased Antithrombin III Activity and Hypocomplementemia on the Gestational Outcomes of Pregnancies with MTHFR Polymorphisms

Erdem Fadiloglu, Hanife Guler Donmez, Kemal Beksac, Mehmet Sinan Beksac · Zeitschrift für Geburtshilfe und Neonatologie · 2023 · Heft 06 · S. 434-440

Dokument
886444
CareLit-ID
Jahr
2023
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Geburtshilfe und Neonatologie
Autor:innen
Erdem Fadiloglu, Hanife Guler Donmez, Kemal Beksac, Mehmet Sinan Beksac
Ausgabe
Heft 06 / 2023
Jahrgang 227
Seiten
434-440
Erschienen: 2023-12-01 00:00:00
ISSN
0948-2393

Zusammenfassung

Abstract Objective To evaluate the impact of increased Activated Protein C (APC) resistance, decreased antithrombin III activity and hypocomplementemia on the pregnancy outcomes of the patients with methylentetrahydrofolate reductase (MTHFR) polymorphisms. Methods This study was composed of 83 pregnancies with MTHFR polymorphisms. Increased APC resistance, decreased antithrombin III activity and hypocomplementemia were accepted as risk factors for poor gestational outcome. Results Having at least one risk factor resulted in significantly higher rates of “APGAR score of

Schlagworte

pregnancy mthfr polymorphisms Activated Protein C resistance Antithrombin III activity hypocomplementemia Zeitschrift für Geburtshilfe und Neonatologie