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Impact of 68Ga-PSMA PET/CT on radiation treatment planning of prostate cancer patients

Laura Schubert, Hannes Rennau, Jens Kurth, Bernd J. Krause, Guido Hildebrandt, Sarah Marie Schwarzenböck · Nuklearmedizin - NuclearMedicine · 2024 · Heft 03 · S. 199-206

Dokument
905657
CareLit-ID
Jahr
2024
Publikation
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Nuklearmedizin - NuclearMedicine
Autor:innen
Laura Schubert, Hannes Rennau, Jens Kurth, Bernd J. Krause, Guido Hildebrandt, Sarah Marie Schwarzenböck
Ausgabe
Heft 03 / 2024
Jahrgang 63
Seiten
199-206
Erschienen: 2024-06-01 00:00:00
ISSN
0029-5566
DOI
10.1055/a-2284-0593

Zusammenfassung

Abstract Aim This study aimed to assess the impact of 68Ga-PSMA PET/CT on radiation treatment (RT) planning in prostate cancer patients with salvage (sRT) or definitive (dRT) radiotherapy. Methods 38 patients (27 sRT, median PSA 0.79 ng/ml (range 0.06–12.1); 11 dRT, median PSA 4.35 ng/ml (range 1.55–55.5) underwent 68Ga-PSMA PET/CT before RT. Influence of 68Ga-PSMA PET/CT on the extent of planning target volume (PTV) and addition of PET-based boosts were assessed. Median follow up was 12 months (range 3–24). Results 68Ga-PSMA PET/CT showed positive findings in 23/38 patients (8/23: local recurrence (LR), 11/23:…

Schlagworte

Prostate cancer 68Ga-PSMA PET/CT planning target volume definitive radiotherapy salvage radiotherapy Nuklearmedizin - NuclearMedicine